We do not have enough data on this route to provide a reliable graph showing how many days before departure it is the best to book.
However, usually the closer it is to the departure, the more expensive the tickets are.
The most popular airlines on the route Brindisi - Brussels: Alitalia (AZ).
The cheapest flights are on the route Papola Casale (BDS) - Brussels Intl Airport (BRU).
There is no direct flight on the route from Brindisi to Brussels
Il volo con scalo più breve dura 22h 45min.