For the cheapest flights to Berlin book 49 days before departure.
The most popular airlines on the route Madrid - Berlin: Ryanair (FR), Iberia (IB), Air Berlin (AB).
The cheapest flights are on the route Barajas (MAD) - Schonefeld (SXF).
Direct flights last about 2h 50min.
Direct flights are available 7 days a week.
Direct flights: Ryanair (FR), Air Berlin (AB), Iberia (IB).