We do not have enough data on this route to provide a reliable graph showing how many days before departure it is the best to book.
However, usually the closer it is to the departure, the more expensive the tickets are.
The most popular airlines on the route Santander - Milan: Iberia (IB).
The cheapest flights are on the route Parayas (SDR) - Bergamo Orio al Serio (BGY).
Direct flights last about 2h 15min.
Direct flights available on: Saturday.
Direct flights: Ryanair (FR).